Best-rated hotels in Clarksdale for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

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Why book with us?

Choose from exclusive hotel collection

We offer thousands of Clarksdale hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

Enjoy seamless booking experience

Once you choose your best place to stay, take a minute to complete a quick reservation form and get an instant confirmation letter to your email address.

Benefit from flexible travel options

We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.

Find a hotel

Hotels by class
2 stars 1
Unrated 8
Accommodation type
Hotels 2
Guest house 1
Aparthotel 1
Motel 1
Inn 1
Villa 1
Hostel 1
Thematic Hotels
Luxury accommodations 11
Vacation Rentals 7
Extended Stay 7
Private Villas 6
Pet-friendly hotels 4
Hotels with indoor pool 2
Exceptional design hotels 2
Sustainability certification 1
Jacuzzi 1
Business hotels 1

Hotels by location

Nearby
Coahoma Community College Clarksdale 14
Landmarks
Popular attractions

Welcome to Clarksdale

Discover the birthplace of the blues in the vibrant city of Clarksdale, Mississippi. Immerse yourself in the rich musical heritage that resonates through its streets. Explore iconic juke joints, experience soulful live performances, and indulge in delicious Southern cuisine. Uncover the raw energy that breathes life into this captivating town. Come, experience the magic of Clarksdale and let the blues be your guide.

What our users say about Clarksdale hotels

9.8

Exceptional

us John 24 December 2022
This place was cool, with its cozy rooms and an awesome location. The staff were really nice and welcoming. 👍
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9.8

Exceptional

us Ray 24 December 2022
The location was great, just a 5-minute walk to the casinos. It was in a lovely area near the Margaritaville restaurant. This made it a convenient base for my stay.
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9.8

Exceptional

us William 24 October 2022
The hotel was fairly clean. Facilities were clean. - Marvellous location just off the casino. - the food was appetising with plenty of alternatives. - Nothing too much trouble. - Appreciated my stay at this venue.
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9.8

Exceptional

us Karl 29 December 2022
The whole experience was amazing! Loved my 2 nights stay. - Booked a room with awesome views of the beach. - Every staff member was wonderful and pleasant. - My check in was good.
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9.8

Exceptional

us Paul 24 January 2023
The location of the hotel was great, as it was close to the casino in Biloxi. Additionally, the hotel was conveniently situated near the Hurricane Katrina Memorial. The room had fantastic views and provided a pleasant atmosphere for my three-night stay. The breakfast offered was consistently delicious and of high quality.
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9.8

Exceptional

us Clifford 15 September 2022
the hotel is clean with courteous staff. the breakfast was amazing and had a 4-star level. 3. the room was gorgeous, relaxing, and had a great view. 4. the room came with extra towels and shower caps.
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9.8

Exceptional

us Marcus 19 July 2022
The hotel was upscale with delicious and affordable breakfasts. I got a well-maintained room with a private bathroom. the venue had a gorgeous location near St Michael's Catholic Church. I loved the indoor restaurants around.
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9.8

Exceptional

us Donna 26 April 2023
Trendy building, rooms nicely done with a lovely view 😊.
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9.8

Exceptional

us Alexander 27 January 2023
This place was fantastic, situated right by the river, in a peaceful location close to Natchez Gazebo and near the city center and a casino.
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9.8

Exceptional

us John 16 March 2022
This place was comfortable for exploring the area, and we liked it because we got a room with a bath.
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Save time on your trip arrangements by booking one of our hand-picked hotels

Best 4-star hotels
Exclusive 3-star hotels
Quality 2-star hotels
Experience the best value for your money by checking out our selection of 4-star Clarksdale hotels.
Pool House Hotel

132 Mcguire Cove, Clarksdale, United States

Excellent
27 reviews

196 US$

min. price/night

The Lofts At The Five & Dime Aparthotel

211 Yazoo Avenue, Clarksdale, United States

173 US$

min. price/night

Enjoy truly authentic experiences without compromising comfort and convenience.
Clark House Inn

211 Clark Street, Clarksdale, United States

Excellent
502 reviews

135 US$

min. price/night

Hampton Inn Clarksdale, Ms

15000 New Africa Road, Clarksdale, United States

Good
208 reviews

119 US$

min. price/night

America'S Best Value Inn Clarksdale

350 South State Street, Clarksdale, United States

Good
141 reviews

69 US$

min. price/night

Quality Inn Clarksdale

818 South State Street, Clarksdale, United States

Average
1 review

85 US$

min. price/night

Discover the hidden gems of Clarksdale by booking one of its budget-friendly hotels.
Travelers Hotel

212 3Rd Street, Clarksdale, United States

Excellent
157 reviews

155 US$

min. price/night

Travelers’ choice

Check out the most booked accommodations to find reliable places that our users have tried and tested.
Hostel Auberge Clarksdale

164 Delta Avenue, Clarksdale, United States

Excellent
148 reviews

109 US$

min. price/night

The Governor'S Mansion - A Step Back In Time. Villa

41 John Street, Clarksdale, United States

Excellent
14 reviews

417 US$

min. price/night

Delta Dream Retreat Villa

1046 Barnes Avenue, Clarksdale, United States

Excellent
9 reviews

Sunflower Cottage On The River

226 Luster Lane Sunflower Cottage, Clarksdale, United States

Good
8 reviews

212 US$

min. price/night

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