Best-rated hotels in Greenville for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

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Choose from exclusive hotel collection

We offer thousands of Greenville hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

Enjoy seamless booking experience

Once you choose your best place to stay, take a minute to complete a quick reservation form and get an instant confirmation letter to your email address.

Benefit from flexible travel options

We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.

Find a hotel

Hotels by class
2 stars 4
Unrated 1
Accommodation type
Hotels 9
Inn 1
Motel 1
Lodge 1
Thematic Hotels
Pet-friendly hotels 5
Casino hotels 4
Luxury accommodations 4
Business hotels 4
Airport hotels 4
Luxury hotels 3
Hotels with indoor pool 3
Resorts 2
Extended Stay 2
Beach hotels 1
Spa hotels 1
Sustainability certification 1
Jacuzzi 1
Boutique hotels 1
Golf hotels 1
Vacation Rentals 1
Historical hotels 1
Exceptional design hotels 1

Hotels by location

Nearby
Mid-Delta Regional Airport 4
Greenville Higher ED Ctr 1
Winterville Mounds State Park 4
Greenville Park Commission 7
Delta Area Health Education Greenville 8
Reed-Joseph International CO 8
Nelson's Street Sports Parlor Greenville 8
Real 4 Life Inc Greenville 2
Greenville Arts Council 8
Monte Carlo Recreation Greenville 8
Mainstream Mall Shopping Center 8
Washington County Convention Center 4
Lighthouse Point Casino 9
Greenville Park Office 8
Gray's Bowling Lanes Inc Greenville 9
Diamond Jim's Greenville 9
Casablanca Inn Greenville 8
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Welcome to Greenville

Looking to explore a vibrant city nestled amidst the stunning Blue Ridge Mountains? Look no further than Greenville, where Southern charm meets modern elegance. Discover a thriving art scene, mouthwatering cuisine, and a bustling downtown with trendy shops and lively bars. Immerse yourself in the rich history and natural beauty of Falls Park on the Reedy. Experience the magic of Greenville for yourself and make unforgettable memories in this captivating city.

What our users say about Greenville hotels

9.8

Exceptional

us John 24 December 2022
This place was cool, with its cozy rooms and an awesome location. The staff were really nice and welcoming. 👍
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9.8

Exceptional

us Ray 24 December 2022
The location was great, just a 5-minute walk to the casinos. It was in a lovely area near the Margaritaville restaurant. This made it a convenient base for my stay.
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9.8

Exceptional

us William 24 October 2022
The hotel was fairly clean. Facilities were clean. - Marvellous location just off the casino. - the food was appetising with plenty of alternatives. - Nothing too much trouble. - Appreciated my stay at this venue.
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9.8

Exceptional

us Karl 29 December 2022
The whole experience was amazing! Loved my 2 nights stay. - Booked a room with awesome views of the beach. - Every staff member was wonderful and pleasant. - My check in was good.
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9.8

Exceptional

us Paul 24 January 2023
The location of the hotel was great, as it was close to the casino in Biloxi. Additionally, the hotel was conveniently situated near the Hurricane Katrina Memorial. The room had fantastic views and provided a pleasant atmosphere for my three-night stay. The breakfast offered was consistently delicious and of high quality.
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9.8

Exceptional

us Clifford 15 September 2022
the hotel is clean with courteous staff. the breakfast was amazing and had a 4-star level. 3. the room was gorgeous, relaxing, and had a great view. 4. the room came with extra towels and shower caps.
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9.8

Exceptional

us Marcus 19 July 2022
The hotel was upscale with delicious and affordable breakfasts. I got a well-maintained room with a private bathroom. the venue had a gorgeous location near St Michael's Catholic Church. I loved the indoor restaurants around.
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9.8

Exceptional

us Donna 26 April 2023
Trendy building, rooms nicely done with a lovely view 😊.
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9.8

Exceptional

us Alexander 27 January 2023
This place was fantastic, situated right by the river, in a peaceful location close to Natchez Gazebo and near the city center and a casino.
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9.8

Exceptional

us John 16 March 2022
This place was comfortable for exploring the area, and we liked it because we got a room with a bath.
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Save time on your trip arrangements by booking one of our hand-picked hotels

Best 4-star hotels
Exclusive 3-star hotels
Quality 2-star hotels
Experience the best value for your money by checking out our selection of 4-star Greenville hotels.
Harlow'S Casino Resort & Spa

4280 Harlows Blvd, Greenville, United States

Good
97 reviews

158 US$

min. price/night

Harlows Casino Resort And Spa

4280 Harlows Blvd, Greenville, United States

119 US$

min. price/night

The Lofts At 517 Hotel

517 Washington Avenue, Greenville, United States

213 US$

min. price/night

Belmont Plantation, Est 1857 Bed & Breakfast

3498 Highway 1 South, Greenville, United States

185 US$

min. price/night

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Enjoy truly authentic experiences without compromising comfort and convenience.
Tru By Hilton Greenville

600 Rayner Road, Greenville, United States

Good
256 reviews

130 US$

min. price/night

The Skylight Hotel

745 Washington Avenue, Greenville, United States

99 US$

min. price/night

Hampton Inn Greenville

1155 Vfw Road, Greenville, United States

186 US$

min. price/night

Discover the hidden gems of Greenville by booking one of its budget-friendly hotels.
Days Inn By Wyndham Greenville Ms

2701 Highway 82 East, Greenville, United States

Average
104 reviews

85 US$

min. price/night

Americas Best Value Inn & Suites Greenville

2700 Highway 82 East, Greenville, United States

Average
86 reviews

66 US$

min. price/night

Rodeway Inn Greenville

137 N. Walnut Street, Greenville, United States

79 US$

min. price/night

Holiday Inn Express & Suites Greenville By Ihg

3090 Highway 82 East, Greenville, United States

169 US$

min. price/night

Travelers’ choice

Check out the most booked accommodations to find reliable places that our users have tried and tested.
Econo Lodge Greenville

3080 Us 82 E., Greenville, United States

Average
107 reviews

70 US$

min. price/night

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